Novantrone

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This represents one person's experience on Novantrone. Individual results may vary. For additional safety information read the Patient Information leaflet.

"I knew the symptoms of MS were going to be a lifelong challenge. But when I started not getting back full capability after relapses, I began to wonder if my MS was worsening."

Robert is a former Marine and now teaches in California. He has been living with MS since 1996 and was treated with Novantrone from 2000 to 2002.

more Ambassador stories

Multiple Sclerosis (MS) can be challenging. It can demand constant re-adjustments and new approaches to everyday living. And while you may feel confident about the treatment you're on, you should know the warning signs if your MS begins to worsen.

Worsening MS isn't often talked about, but now it's time.

This site offers facts, and hopefully some comfort, about worsening MS. You will learn what worsening MS is, and what it isn't. You will learn about Novantrone® (mitoxantrone concentrate for injection), the only FDA-approved treatment for worsening MS. You will hear from MS LifeLines^SM Ambassadors, people living with MS, who recognized their MS was worsening and took action. Most importantly, you will get tips for monitoring your MS, and what next steps you can take to slow its progression.

Novantrone for treating Multiple Sclerosis (MS)

Novantrone is used to reduce relapses and disability in patients with the following forms of MS:

secondary (chronic) progressive
progressive relapsing
worsening relapsing-remitting

Novantrone is not for patients with primary progressive MS.

Novantrone can cause the following serious problems:

Novantrone may damage your heart at any time during treatment or months to years after treatment ends. Heart damage from Novantrone can be serious and may cause death. Your chance of heart problems depends on the amount of Novantrone you have used. Your doctor will limit your number of Novantrone doses. Your doctor will do certain tests to see if your heart is normal:
- before you start Novantrone
- before each dose of Novantrone
if you have symptoms of heart problems during and after treatment with Novantrone
Novantrone can increase your chance of getting an infection.
Patients treated with Novantrone have an increased chance of developing leukemia.

Novantrone should not be used:

by women who are pregnant or trying to get pregnant
if your heart's ability to pump blood is decreased
if you have a low number of white blood cells
if you are allergic to Novantrone

Before taking Novantrone, tell your doctor about your past and current health conditions including:

heart disease
cancer treatment
radiation to the chest
blood-clotting or bleeding problems
low blood counts
infections
liver disease or problems

Tell your doctor about all the medicines you take. Tell your doctor if you ever had treatment with Novantrone.

The most common side effects of Novantrone in patients with MS are nausea, hair thinning, loss of menstrual periods, mouth sores, and bladder infections.

For more information, read the Novantrone Patient Information leaflet. Talk to your doctor about questions or concerns with Novantrone treatment.

The health information contained herein is provided for educational purposes only and is not intended to replace discussions with a healthcare provider. All decisions regarding patient care must be made with a healthcare provider, considering the unique characteristics of the patient.

This information is intended only for residents of the United States.